| Product: | Pidotimod | |
|---|---|---|
| Catalog Number: | 32281 | |
| CAS Number: | 121808-62-6 | |
| Pricing: |
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| Formula: | C9H12N2O4S | |
| Chemical Purity: | >98% | |
| Molecular Weight: | 244.27 | |
| Structure: |  | |
| Appearance: | White powder | |
| Category: | API Compounds | |
| Stability: | Stable under recommended storage conditions | |
| Storage: | Store at 4°C | |
| Literature References: | Migliorati, G., et al. 1994. Arzneimittelforschung. 44: 1421-1424;Gourgiotis, D., et al. 2004. J Asthma. 41: 285-287;Riboldi, P., et al. 2009. Int J Immunopathol Pharmacol. 22: 255-262;Giagulli, C., et al. 2009. Int. Immunopharmacol. 9: 1366-1373. | |
| MSDS: | ||
| Description: | Pidotimod is a synthetic dipeptide with immunological modulatory activity on both the adaptive and innate immune responses. This compound has been shown to induce dendritic cell maturation and up-regulate the expression of HLA-DR and co-stimulatory molecules CD83 and CD86, which are integral to communication with adaptive immunity cells. Pidotimod has also been shown to stimulate dendritic cells to release pro-inflammatory molecules such as MCP-1 and TNF-α cytokines, and to inhibit thymocyte apoptosis caused by a variety of apoptosis inducing molecules |
