| Product: | 4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride | ||||||||
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| Catalog Number: | 16314 | ||||||||
| CAS Number: | 30827-99-7 | ||||||||
| Synonyms: | AEBSF | ||||||||
| Pricing: |
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| Formula: | C8H10FNO2S • HCl | ||||||||
| Chemical Purity: | >97% | ||||||||
| Molecular Weight: | 239.69 | ||||||||
| Structure: |  | ||||||||
| Appearance: | Beige crystalline | ||||||||
| Category: | Biochemicals and Reagents | ||||||||
| Stability: | Stable under recommended storage conditions. | ||||||||
| Storage: | Keep container tightly closed in a dry and well-ventilated place. Store under argon. Recommended storage temperature: -20°C. Moisture sensitive | ||||||||
| Transportation: | IATA: Hazard Class: 8; UN Number: UN3261; Packing Group: II; Shipping Name: Corrosive solid, acidic, organic, n.o.s. (4-(2-Aminoethyl)benzenesulfonylfluoride hydrochloride) | ||||||||
| Literature References: | Baker, B.R. and Cory, M. J. Med. Chem. 14, 119, (1971);Markwardt, F., et al. Thromb. Res. 2, 343, (1973); Lunn, G. and Sansone, E.B. Appl. Biochem. Biotechnol. 48, 57, (1994); Mintz, G.R. BioPharm. 6, 34, (1993); Lawson, W.B., et al. Folia Haematol. 109, 52, (1982); Markwardt, F., et al. Biochem. Pharmacol. 23, 2247, (1974) | ||||||||
| MSDS: | |||||||||
| Description: | Irreversible serine protease inhibitor. Inhibition constants are similar to those of PMSF and DFP. AEBSF has been shown to inhibit trypsin, chymotrypsin, plasmin kallikrein and thrombin. As an alternative to PMSF and DFP, AEBSF offers lower toxicity, improved solubility in water and improved stability in aqueous solutions. AEBSF has been used in cell culture in concentrations of up to 0.25 mM. |
