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商品详细Medica Lisotopes/Doxorubicin HCl/10 mg/9812-10 mg
Medica Lisotopes/Doxorubicin HCl/10 mg/9812-10 mg
Medica Lisotopes/Doxorubicin HCl/10 mg/9812-10 mg
商品编号: 9812-10mg
品牌: medicalisotopes
市场价: ¥3800.00
美元价: 3040.00
产地: 美国(厂家直采)
公司:
产品分类: 聚合物
公司分类: juhewu
联系Q Q: 3392242852
电话号码: 4000-520-616
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商品介绍
Product:Doxorubicin HCl
Catalog Number:9812
CAS Number:25316-40-9
Synonyms:(8S,10S)-10-[(3-Amino-2,3,6-trideoxy-α-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione;
Adriacin;
Adriblastina;
Adriamycin;
Caelyx
Pricing:
10 mg=$190(In Stock)
50 mg=$690(In Stock)
100 mg=$850(In Stock)
Formula:C27H31ClNO11
Chemical Purity:99%
Molecular Weight:579.98
Structure:Doxorubicin HCl
Appearance:Orange to dark orange-red powder
Category:Antibiotics
Stability:Stable under recommended storage conditions.
Storage:

Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature 2-8 °C. Moisture sensitive. Light sensitive

Transportation:

Non-hazardous for transport

Literature References:

C.N. Ellis et al. Biochem. J. 245, 309, (1987);R.J. White et al. Drugs Pharm. Sci. 22, 569, (1984);A. Vigevani, M.J. Williamson Anal. Profiles Drug Subst. 9, 245, (1980); Gong, Y., et al. J. Biol. Chem. 278, 50234-50239, (2003); Rajagopal, A., and Simon, S.M. Mol. Biol. Cell 14, 3389-3399, (2003); Venkatachalam, K., et al., Neutralization Of Interleukin-18 Ameliorates Ischemia/reperfusion-induced Myocardial Injury. J. Thorac. Cardiovasc. Surg. 284, 7853-65, (2009); Park, J.Y., et al., Doxorubicin Enhances CD4(+) T-cell Immune Responses By Inducing Expression Of CD40 Ligand And 4-1BB. Int. Immunopharmacol. 9, 1530-9, (2009); Simpson, N.E., et al., High Levels Of Hsp90 Cochaperone P23 Promote Tumor Progression And Poor Prognosis In Breast Cancer By Increasing Lymph Node Metastases And Drug Resistance. Cancer Res. 70, 8446-56, (2010); Benson, E.K., et al., Role Of Progerin-induced Telomere Dysfunction In HGPS Premature Cellular Senescence. J. Cell Biol. 123, 2605-12, (2010); Ahn, J., et al., Srg3, A Mouse Homolog Of BAF155, Is A Novel P53 Target And Acts As A Tumor Suppressor By Modulating P21(WAF1/CIP1) Expression. Oncogene 30, 445-56, (2011); Cheng, J., et al., Poly(ethylene Glycol)-conjugated Multi-walled Carbon Nanotubes As An Efficient Drug Carrier For Overcoming Multidrug Resistance. Toxicol. Appl. Pharmacol. 250, 184-93, (2011); Friesen, C., et al., Cytotoxic drugs and the CD95 pathway. Leukemia 13, 1854, (1999); Kraus-Berthier, L, et al., Histology and sensitivity to anticancer drugs of two human non-small cell lung carcinomas implanted in the pleural cavity of nude mice. Clin. Cancer Res. 6, 297-304, (2000); Sparano, J.A., Doxorubicin/taxane combinations: cardiac toxicity and pharmacokinetics. Semin. Oncol. 26, 14-19, (1999)

MSDS:
Click here.
Applications:Used in cancer chemotherapy as an anthracycline antitumor antibiotic. Intercalates DNA. Used as a treatment in a wide range of cancer such as, hematological malignancies, many types of carcinomas, and soft tissue sarcomas
品牌介绍
Medical Isotopes的化学家是他们领域的专家,在合成稳定同位素标记化合物方面拥有多年的经验。当需要特殊设计的特殊化合物时,Medical Isotopes拥有专业资源来合成所需的定制化合物。活化剂活化剂是一种可以提高另一种活性物质的物质。例如,微量的物质赋予晶体发光; 硫化锌或硫化镉颜料中的银或铜。在遗传学中,它将是一种以使其能够刺激操纵子转录的方式修饰阻遏物的分子。活化剂的实例是:1-乙酰氨基-4-氰基-3-甲基异喹啉,其用作环AMP依赖性蛋白激酶(PKA)的选择性抑制剂,而D-赤型 - 二氢-D-鞘氨醇用作生物合成前体。鞘氨醇,抑制蛋白激酶C. Product:(Acetylamino)[(3-methoxy-5-methyl-4-isoxazolyl)methyl]propanedioic Acid Diethyl EsterCatalog Number:38430CAS Number:75989-23-0Pricing:10 mg = $650  100 mg = $2,200   Formula:C15H22N2O7Molecular Weight:342.340Category:Chemical Activators
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