Product: | Cantharidin | ||||||
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Catalog Number: | 17402 | ||||||
CAS Number: | 56-25-7 | ||||||
Synonyms: | 3a,7a-Dimethylhexahydro-4,7-epoxyisobenzofuran-1,3-dione; 7a-Dimethylhexahydro-3a,4,7-epoxyisobenzofuran; Hexahydro-3a,7a-dimethyl-4,7-epoxyisobenzofuran-1,3-dione | ||||||
Pricing: |
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Formula: | C10H12O4 | ||||||
Molecular Weight: | 196.20 | ||||||
Structure: | |||||||
Appearance: | Solid | ||||||
Category: | Anti-cancer compounds | ||||||
Stability: | Stable under recommended storage conditions. | ||||||
Storage: | Keep container tightly closed in a dry and well-ventilated place. Light sensitive | ||||||
Transportation: | IATA: Hazard Class: 6.1; UN Number: UN2811; Packing Group: I; Shipping Name: Toxic solids, organic, n.o.s. ((1R,2S,3R,6S)-1,2-Dimethyl-3,6-epoxycyclohexane-1,2-dicarboxylic anhydride) | ||||||
Literature References: | Knapp, et al., The protein phosphatase inhibitor cantharidin alters vascular endothelial cell permeability. J. Pharmacol. Exp. Ther. 289, 1480-1486, (1999); Knapp, et al., Contractility and inhibition of protein phosphatases by cantharidin. Gen. Pharmacol. 31, 729-733, (1998); Krieser, et al., Cleavage and nuclear translocation of the caspase 3 substrate Rho GDP-dissociation inhibitor, D4-GDI, during apoptosis. Cell Death Differ. 6, 412-419, (1999); Baskin, T.I., and Wilson J.E., Inhibitors of protein kinases and phosphatases alter root morphology and disorganize cortical microtubules. Plant Physiol. 113, 493-502, (1997); Merck 14,1752; Beil. 19,161; FT-IR 2 (1), 1214:C / Structure Index 1, 130:D:1 | ||||||
MSDS: | |||||||
Description: | Inhibitor of protein phosphatase 2A. |