| Product: | Bisantrene | |
|---|---|---|
| Catalog Number: | 17382 | |
| CAS Number: | 71439-68-4 | |
| Synonyms: | Bisantrene dihydrochloride | |
| Pricing: |
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| Formula: | C22H22N8 • 2HCl | |
| Chemical Purity: | >98% | |
| Molecular Weight: | 471.39 | |
| Structure: |  | |
| Appearance: | Solid | |
| Category: | Anti-cancer compounds | |
| Stability: | Stable under recommended storage conditions. | |
| Storage: | Keep container tightly closed in a dry and well-ventilated place | |
| Transportation: | IATA: Hazard Class: 6.1; UN Number: UN2811; Packing Group: III; Shipping Name: Toxic solid, organic, n.o.s. (Bisantrene dihydrochloride) | |
| Literature References: | Xie, SQ.,et al., Anti-tumour effects of HL-37, a novel anthracene derivative, in-vivo and in-vitro J. Pharm. Pharmacol. 60, 213 - 219, (2008); Robey, RW., et al., Mutations at amino-acid 482 in the ABCG2 gene affect substrate and antagonist specificity Br. J. Cancer 89, 1971 - 1978, (2003); Litman, T., et al., The multidrug-resistant phenotype associated with overexpression of the new ABC half-transporter, MXR (ABCG2) J. Cell Sci. 113, 2011 - 2021, (2000); Merck 14,1244 | |
| MSDS: | ||
| Description: | Bisantrene dihydrochloride is an antineoplastic agent, MDR1 substrate, DNA intercalator and topoisomerase II poison |
