| Product: | D-erythro-Sphingosine-1-Phosphate | ||||||||
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| Catalog Number: | 13515 | ||||||||
| CAS Number: | 26993-30-6 | ||||||||
| Synonyms: | Sphingosine 1-phosphate | ||||||||
| Pricing: |
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| Formula: | C18H38NO5P | ||||||||
| Chemical Purity: | >95% | ||||||||
| Molecular Weight: | 379.47 | ||||||||
| Structure: |  | ||||||||
| Appearance: | Powder | ||||||||
| Category: | Chemical Activators | ||||||||
| Stability: | Stable under recommended storage conditions. | ||||||||
| Storage: | Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20°C. | ||||||||
| Transportation: | Non-hazardous for transport | ||||||||
| Literature References: | Byfield, F.J., et al., Cathelicidin LL-37 Peptide Regulates Endothelial Cell Stiffness And Endothelial Barrier Permeability. Am. J. Physiol. Cell Physiol. 300, C105-12, (2011); Panetti, T.S., Differential effects of sphingosine 1-phosphate and lysophosphatidic acid on endothelial cells. Biochim. Biophys. Acta 1582, 190-196, (2002); Mattie, M., et al., Sphingosine-1-phosphate: a putative second messenger mobilizes calcium from internal stores via an inositol trisphosphate-independent pathway. J. Biol. Chem. 269, 3181, (1994) | ||||||||
| MSDS: | |||||||||
| Description: | A lipid second messenger that binds to S1P1 and S1P3 receptors. Mobilizes intracellular Ca2+ stores and decreases cellular cAMP. Activates phospholipase D. S1P stimulates the migration of endothelial cells but inhibits the migration of other cell types. Induces angiogenesis |
